How edibles work — the slow-onset science
When you smoke or vape cannabis, THC enters the bloodstream through the lungs and effects start within minutes. When you eat cannabis, THC has to pass through the digestive tract and the liver, where it's converted to a different metabolite (11-hydroxy-THC) — a process that takes much longer.
Per peer-reviewed research published in PubMed Central (Barrus et al., "Tasty THC: Promises and Challenges of Cannabis Edibles" — see Sources): "Peak responses occur an average of 3 hours after ingestion and effects dissipate within 24 hours." This is significantly different from inhaled cannabis where effects occur almost immediately.
The same paper notes the safety implication: "Consumers often do not understand this aspect of edible use and may consume a greater than intended amount of drug before the drug has taken effect, often resulting in profoundly adverse effects." That's why every Happy Time budtender repeats the dosing rules to first-time edibles customers.
